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Course offering number:0810-201

Course ID:
2163
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Role of PAT and QbD in Biologic Drug Production
9-10 October 2008
Amsterdam

Who Should Attend
This comprehensive quality system workshop will benefit professionals who are involved in the entire biologic drug chain, from development, through unit operations to product fill, storage and release to market, including:

  • PAT and QbD Team Leaders and Members
  • Quality and Efficiency Personnel
  • Manufacturing Operations Personnel
  • Product Development Teams
  • Technology Transfer Personnel
  • In-process and Finished Goods Analysts
  • Biologic Excipient Suppliers
  • Analytical Instrument and Manufacturing Equipment Suppliers
  • Managers tasked with biologic product development and evolution

Description
PAT – Process Analytical Technology is a risk management approach for ensuring consistent production of prescription drugs within a well-defined quality envelope. QbD – Quality by Design – encompasses PAT and uses its concepts across a much wider front; from drug discovery and development to the patient. Both PAT and QbD are mainstays of 21st century good manufacturing practice.

This course establishes an operating baseline for biologic PAT programs, using the outcomes of successful small-molecule PAT efforts. Course modules include an analysis of biologic business drivers and timelines, PAT and QbD principles and their relationship to the ICH – International Conference on Harmonization.

The course includes sections on biologic unit operations, in-process testing and supra-process testing - including the use of dynamic test technologies to support mainstream production methods.




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