Course offering number:0809-705
Course ID:
2236
Lyophilization 101: Principles, Physical Properties and Characterization Techniques
Pre-recorded Course
90 Minute Accredited Online Training
Who Should Attend
This course is designed for personnel in the pharmaceutical, diagnostic, biomedical engineering and biotechnology industries including:-
Biochemists/Chemists
- Chemical Engineers
- Microbiologists
- Pharmacists
- R&D personnel
- Pilot Plant Operations
- Production Supervisors
- QA/QC professionals
- Managers
Description
This 90-minute accredited online course is designed to provide an introduction to the basic scientific and engineering principles of freeze-drying. In addition, this course will provide insight into characterizing and understanding the thermal properties of the formulation through techniques such as differential scanning calorimetry (DSC) and freeze-dry microscopy.
By understanding the complete thermal picture of the formulation, the process development scientist will be able to develop optimized, robust lyophilization cycles in a much more efficient manner in addition to being able to troubleshoot and correct problematic cycles and formulations more effectively.
Module 1: INTRODUCTION TO FREEZE DRYING
• Basic theory
• Basic system components
• Temperature monitoring devices
• Vacuum monitoring devices
Module 2: PHYSICAL PROPERTIES OF MATERIALS
• Crystalline, amorphous, and mixed systems
• Eutectic melts, glass transitions, and collapse
temperatures
• Physical loss of structure: collapse and meltback
• Examples of failed products
Module 3: MATERIALS CHARACTERIZATION TECHNIQUES
• Principles of thermal analysis
• Thermal analysis equipment
• Freeze-dry microscopy equipment and techniques
• Applications of thermal analysis and freeze-dry microscopy
for frozen and dried systems
• Question and Answer Session