Pilot Plant and Scale-up Studies
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Who Should Attend
Engineers and scientists who are involved with process
development, process translation, scale-up and pilot plant studies
will benefit from this course. This includes those in:
• Pilot plant operations
• Specialty chemical production
• Food processing
• Chemical reactor design
• Waste processing
• Pharmaceutical production
• Process and project design
• Composite material manufacturing
• Biotechnology and fermentation
Description
This course will provide concepts, methods and advice on how to
scale-up or translate a process or model to larger sizes.
Emphasis throughout the course will be on proper designs,
modeling and processing. The importance of the process
geometry will be emphasized.
The course will cover the different scale-up methods and how to
establish viable process objectives. A general scale-up method is
presented and a number of examples are worked as illustrations.
Scale-up traps and pitfalls are reviewed as well as ways to avoid
these. The importance of process objectives will be emphasized.
Basic concepts of importance are reviewed using different areas
as examples. Power analysis will be presented as a useful tool in
scale-up. Examples will show how to use the power analysis in
applications and to establish the controlling mechanisms. Detailed
suggestions for pilot studies will be given. Scale-up in the mixing
and contacting area is reviewed. Equipment, operating conditions,
optimum designs and processing conditions will be discussed.
Methods to perform process translation in mixing will be
developed and examined as to their practicality. Correlations and
data use will be reviewed for process accuracy and use in pilot
studies. Pitfalls and the use of analogies in solving processing
problems will be discussed.
Other Courses of Interest
Biopharmaceutical Process Systems
Elements of Applied Process Engineering
Apr 16 2012, New Brunswick, NJ
Pharmaceutical Process Development
Apr 23 2012, Amsterdam, The Netherlands
Pharmaceutical Technology Transfer
Feb 29 2012, New Brunswick, NJ
Pharmaceutical Technology Transfer
Jun 13 2012, Amsterdam, The Netherlands
Piping Design, Analysis and Fabrication
Process Plant Start-Up
Apr 23 2012, Amsterdam, The Netherlands
Scale-Up and Post Approval Changes Guidelines (SUPAC & API Changes)
Feb 27 2012, New Brunswick, NJ
Scale-Up and Post Approval Changes Guidelines (SUPAC & API Changes)
Jun 11 2012, Amsterdam, The Netherlands
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